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James Mason

Dr. John Polidori

Leonard Whiting

Victor Frankenstein

David McCallum

Dr. Clervall

Jane Seymour

Agatha / Prima

Nicola Pagett

Elizabeth Fanschawe

Michael Sarrazin

The Creature

Michael Wilding

Sir Richard Fanshawe

Tom Baker

Sea Captain

Clarissa Kaye-Mason

Lady Fanschawe

Agnes Moorehead

Mrs. Blair

Margaret Leighton

Francoise DuVal

Ralph Richardson

Mr. Lacey

John Gielgud

Chief Constable

Peter Sallis

Priest

Yootha Joyce

Hospital Matron